Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health

我经常觉得不开心
Besides Edhec and HEC, Essec Business School, ESCP Europe and Skema Business School are in third, fourth and sixth places respectively.
The Nobel Prize in physiology or medicine was awarded to a cellular-level experiment.
除了P2P贷款领域发展迅速以外,今年还涌现出一些网络银行和贷款机构——比如腾讯(Tencent)的微众银行(WeBank)、阿里巴巴(Alibaba)的网商银行(Mybank),以及蚂蚁金融(Ant Financial)的芝麻贷(Sesame Credit)。
The U.S. has fallen to become Germany's third largest trading partner in 2016.
The wealth and depth of knowledge from around the world adds tremendous value to the course, wrote another graduate from the US, adding that “with so many cultures and experiences represented, a classroom ethics discussion about bribery is not your typical boring USA version”.
Haruhiko Kuroday, the Japanese central bank governor said: “I think we can be cautiously optimistic about the global outlook.
The Suicide Squad is scheduled for an August 5th 2016 release.
新兴市场需求减弱使2015年成为全球金融危机爆发以来世界贸易最糟糕的一年,凸显出对于全球经济健康的担忧加深。
7成以上受访者表示,实现自我价值是创业的最大动机。
That’s a lot of issue-related messaging to pack into a single color trend (or even two), but the Pantone statement says it’s the company’s job to reflect social trends and capture them in a shade — which will then become part of the fabrics of our lives, as it were.
但“平均”讲的是以前的情况,不是未来的事实。乐观言论不会让牛市重启,新的警告声音也不会刺破旧的泡沫。周期有自己的生命,该上行的时候上行,该下行的时候下行。这是很自然的事情。
《乐高蝙蝠侠大电影》
指数:100.0
stressful
愿新年不仅是你欢笑的时刻,更是你欣喜的日子。祝福你。
以美元值计,11月中国的进口总值同比上升17.7%,比10月的17.2%高,高于11.3%的预期增速。
认为西方民主政体不会受影响将是愚蠢的。
['k?mb?t]
The director Bennett Miller saw Mr. Carell as a good choice to play du Pont but didn’t want him to be too recognizable. He charged the makeup designer Bill Corso with the task of altering Mr. Carell’s look.
[slu:]
Mr Draghi hit back the day after the December vote, saying that there was no “limit” to what eurozone policymakers could do to return inflation to its target.
stick
It might be that bit too far from the mainstream to make a huge awards impact.
n. 示范,实证,表达,集会


在过去的二十年里,几起校园中毒事件引发了群众对学生心理发展及帮助的争论和关注。
Do you often feel gloomy and down in the dumps?
该学校校友的总体满意度为95%,比伦敦商学院(London Business School)和德国WHU奥拓贝森管理研究院(WHU Beisheim)高出两个百分点。


With the increasing proliferation and sophistication of mobile phones, wearable devices such as smart watches, and sensors that can measure and gather a variety of data, public interest is growing in using consumer electronics to take ownership of personal health and wellness. A 2015 survey found that 66% of Americans age 66 and older want to use mobile technologies to improve their health by receiving medication reminders and tracking diet and nutrition, physical activity, and symptoms.[1

1. What big brother is eating isn’t noodles, but loneliness.
The CHIP, which retails for $150, can only bake four full-sized cookies at a time. If you were go the traditional way and bake a large batch in the oven, you'd have anywhere between eight and 12 cookies in under 30 minutes — and it's also cheaper.
Yes, even if real GDP growth does not. Speculation over the true GDP growth rate in China, as opposed to the official one, has spawned a cottage industry of specialist economists. The official figures are deceptively stable and serene thanks to suspected “smoothing” by the Chinese authorities, as they bend the figures to fit growth targets. So even if growth does stumble in 2018, the official growth rate is almost certain to come in above the preordained 6.5 per cent.
A lot of the best James Bond theme songs sound like they belong in a lounge act. That's not a complaint, just an observation. For whatever reason, the English new wave act Duran Duran was given free reign to provide A View to a Kill with a new and exciting sound all its own. "A View to a Kill" was a hit song, and it probably would have been a success even without the James Bond connection. It's entertaining and cool and energetic, and it promises one hell of a good time. (Whether or not the movie actually lives up to that promise is a matter of some debate.)

Health apps and wearables
Health apps and wearables can unobtrusively gauge physiological and emotional states and collect, quantify, and monitor data regarding a user’s day-to-day behaviors. This “quantified self” can increase users’ self-awareness regarding their behavior and encourage positive changes to their overall health and well-being.[2] These commercially available devices also integrate an array of features to provide motivation through reward systems, opportunities for social in-teraction, tools for self-improvement, and prompts. The novelty, affordability, practicality, and ease of use have resulted in increased consumer enthusiasm and the pervasiveness of these devices.[3,4] With this growing interest in personal health, members of the general public are becoming more involved in monitoring and improving their own health habits.[5-10

Undoubtedly, merely tracking data through a device is not enough to maintain good health-related behaviors long-term, and the software must also incorporate motivational constructs important for the adoption and habituation of behaviors. For instance, a systematic review of studies that considered the use of electronic activity monitor systems found short-term changes in physical activity with self-monitoring, but no demonstration of superiority when the systems were compared with other interventions.[11] Another review of studies on the viability of using mobile technology for measuring and influencing physical activity found that most apps allow users to document their activity, set goals, review real-time feedback, connect to a social support network, and access online expertise.[12] However, less common among these apps were prompts to act and opportunities for problem solving and action planning, which are crucial constructs that translate intention into long-term behavior change.[13]

Sensor technologies
Sensor technologies have begun to enter the telehealth landscape and are primarily focused on continuous monitoring and precise diagnostics to inform management of various health conditions and diseases.[14-17] Sensors can be integrated into a watch or arm band or adhesive bandages and clothing, and then programmed to collect data on cardiac rhythm, heart rate, blood pressure, respiration, oxygen saturation, galvanic skin response, glucose levels, body temperature, body motions, ambient temperature, and global positioning. For health care providers, sensor inputs can permit remote monitoring, real-time teleconferencing, and timely care for patients with chronic diseases. For both patients and clinicians, telehealth supported by sensors can have profound implications. Clinicians can provide timely and patient-centred care to those living at a distance with chronic disease and can coordinate care when multiple providers are involved, reducing costs to the health care system.

A current clinical example is the management of paroxysmal atrial fibrillation with a mobile ECG and app that monitors the patient’s electrical rhythm to detect frequency and patterns of arrhythmias, and may even allow patients to share ultrasound and electrocardiogram data with their health care provider.[18-20] Telemonitoring with sensors can also support self-management of chronic diseases and detect early signs of deterioration in health requiring immediate treatment and advice.[21] Studies to date have demonstrated some clinical promise for the use of home telemonitoring in the context of heart failure and diabetes. A recent Cochrane review found that telemonitoring was an effective way to lower levels of glycated hemoglobin and low-density lipoprotein.[22] Although several studies on heart failure have produced conflicting results regarding the overall benefits of home monitoring,[23-26] systematic reviews have suggested that home telemonitoring reduces all-cause mortality and hospitalizations, and improves quality of life compared with usual care.[22,27] In addition, features such as automated and mobile telemonitoring appear to be more effective compared with other forms of home telemonitoring.[27]

Further studies are needed to determine how home health monitoring can improve patient safety during the transition from acute care to community care, and to examine the impact of home monitoring on health care costs. TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), an initiative of the University of British Columbia and Vancouver Coastal Health, is seeking to do this with prospective trials designed to uncover how telemonitoring can support the safety of heart failure patients discharged from hospital to home.[28]

Mobile apps, wearables, and sensors in the clinical setting
Even though mobile apps, wearables, and sensor technologies are promising, further research is needed to validate their use and long-term impact.[29] This research will require the collaboration of clinicians, health researchers, engineers, and computer scientists.[30] Understanding the possible risks of using these technologies, from physiological harm to breaching of privacy and confidentiality with insecure devices, and how to mitigate any risks is also important. Other important issues to consider include patient anxiety with overuse of technologies, health data piracy, self-diagnosis resulting from overreliance on self-monitoring, and patients not seeking help appropriately. These technologies should be used only as complementary tools in the treatment and prevention of health conditions and disease and should not be used in isolation by patients who self-diagnose and self-manage without consulting a health professional. 

报告同时也显示,双十一已经成为由淘宝,天猫,京东领衔的电商的最大购物活动。

Instant Heart Rate by Azumio.[31] A free app downloadable to both Apple and Android operating systems that measures heart rate and displays a monitoring strip. As well as helping users accurately track their heart rates, the app is capable of detecting irregular rhythms when palpitations occur. 

Sleep Time by Azumio.[32] A free app that monitors sleep patterns, sleep efficiency, and also acts as an alarm clock. Users can know how often they go into light and deep sleep, and recognize how much of these types of sleep will be necessary for them to feel rested, thereby quantifying the amount of true sleep they need and not just how long they should stay in bed. 

Bellybio Interactive Breating by RelaxLine.[33] A free app that helps users pace their breathing to achieve calmness. Placing the mobile phone against the abdomen, users can follow the sounds emitted to practise deep, abdominal breathing using this simple yet surprisingly effective tool. 

2. “Inside Out” (Pete Docter)
休伊·沃表示,每架飞机每天飞行12到16个航段,每个航班晚点都很容易造成当天几个航班的延误。为了解决这个问题,航空公司的系统运行和控制中心会在必要时做出调整。这可能涉及到把备用飞机和临时机组成员排入时间表,确保航班的准时到达。

据新华社报道,2015年教育部和其他5个中央政府部门一起组成了一个专门工作组,以保障足球在中国学校里的蓬勃发展。
谎言10:我以为我早就把邮件发出去了。我真的发过了。说谎原因:如果告诉你我觉得这事不重要,我把这事忘了,就会伤害到我俩的关系了。
Investigators have arrested one youth and one 18-year-old in connection to the July 9th shooting.
Ford's F-series pickup, the reigning champion for the last quarter-century, held off a strong challenge from Chevrolet's redesigned Silverado to remain the nation's No. 1 selling vehicle. The race to become the best-selling car, an all-Japanese final, belonged again to the Toyota (TM) Camry, which beat out the Honda (HMC) Accord.
但是受访者也指出,社交媒体使得他们读的书更少了、视力受到影响、睡眠更少、隐私遭到泄露以及其他一些问题。
La La Land producer Jordan Horowitz returned to the microphone after being told about the mix up and said 'Moonlight won Best Picture' and insisting that 'this is not a joke'.

Discernment to determine whether a particular app, wearable, or sensor can be effective.
Expertise and experience to guide patients on the use of technology.
Partnership with patients in pursuit of optimal health through technology use.
Trials to closely monitor benefits and drawbacks.
Humility to recognize that patients may know and invest much more time than physicians in looking for these tools.34

Conclusions
Based on today’s rapid pace of development and public enthusiasm for the technology marketplace, health apps, wearables, and sensors will soon become integral to our patients’ pursuits of good health and will need to be integrated in clinical practice. Physicians must be active agents in these evolutionary times, guiding patients, advocating for evidence to support the use of technologies, and participating in the development and incorporation of technology in patient wellness journeys. Through clinical stewardship and partnership with patients, physicians can use their expertise and experience to guide the growth of innovations into mainstream health care.

Competing interests
Dr Ho receives no personal financial compensation as the principal investigator of TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), a project funded by a Canadian Institutes of Health Research grant. This grant is matched by the Michael Smith Foundation for Health Research and the BC Ministry of Health, with additional support provided by TELUS Health and Sentrian. TELUS Health, Cisco, and Avizia have also provided equipment for display in Dr Ho’s Demonstration and Simulation Studio for Health (DaSSH) at UBC. Mr Yao and Dr Lauscher have no competing interests to declare.


年内房企海外融资额或创纪录 境内融资受限


References

1. Cision PR Newswire. Fifth annual Pulse of Online Health survey finds 66% of Americans eager to leverage digital tools to manage personal health. Posted 24 February 2015. Accessed 28 August 2017. www.prnewswire.com/news-releases/fifth-annual-pulse-of-online-health-survey-finds-66-of-americans-eager-to-leverage-digital-tools-to-manage-personal-health-300039986.html.

2. Swan M. Emerging patient-driven health care models: An examination of health social networks, consumer personalized medicine and quantified self-tracking. Int J Environ Res Public Health 2009;6:492-525.

3. Gao Y, Li H, Luo Y. An empirical study of wearable technology acceptance in healthcare. Ind Manag Data Syst 2010;115:1704-1723.

4. Kim KJ, Shin DH. An acceptance model for smart watches: Implications for the adoption of future wearable technology. Internet Res 2015;25:527-541.

5. West JH, Hall PC, Hanson CL, et al. There’s an app for that: Content analysis of paid health and fitness apps. J Med Internet Res 2012;14:e72.

6. Abroms LC, Padmanabhan N, Thaweethai L, Phillips T. iPhone apps for smoking cessation: A content analysis. Am J Prev Med 2011;40:279-285.

7. Cowan LT, Van Wagenen SA, Brown BA, et al. Apps of steel: Are exercise apps providing consumers with realistic expectations? A content analysis of exercise apps for presence of behavior change theory. Health Educ Behav 2013;40:133-139.

8. Azar KM, Lesser LI, Laing BY, et al. Mobile applications for weight management. Am J Prev Med 2013;45:583-589.

9. Breland JY, Yeh VM, Yu J. Adherence to evidence-based guidelines among diabetes self-management apps. Transl Behav Med 2013;3:277-286.

10. Lyons EJ, Lewis ZH, Mayrsohn BG, Rowland JL. Behavior change techniques implemented in electronic lifestyle activity monitors: A systematic content analysis. J Med Internet Res 2014;16:e192.

11. Lewis ZH, Lyons EJ, Jarvis JM, Baillargeon J. Using an electronic activity monitor system as an intervention modality: A systematic review. BMC Public Health 2015;15:585.

12. Bort-Roig J, Gilson ND, Puig-Ribera A, et al. Measuring and influencing physical activity with smartphone technology: A systematic review. Sports Med 2014;44:671-686.

13. Rhodes RE, Yao CA. Models accounting for intention-behavior discordance in the physical activity domain: A user’s guide, content overview, and review of current evidence. Int J Behav Nutr Phys Act 2015;12:1-14.

14. Chen M, Gonzalez S, Vasilakos A, et al. Body area networks: A survey. Mob Networks Appl 2011;16:171-193.

15. Appelboom G, Camacho E, Abraham ME, et al. Smart wearable body sensors for patient self-assessment and monitoring. Arch Public Health 2014;72:28.

16. Chan M, Estève D, Fourniols JY, et al. Smart wearable systems: Current status and future challenges. Artif Intell Med 2012;56:137-156.

17. Alemdar H, Ersoy C. Wireless sensor networks for healthcare: A survey. Comput Networks 2010;54:2688-2710.

18. Haberman ZC, Jahn RT, Bose R, et al. Wireless smartphone ECG enables large-scale screening in diverse populations. J Cardiovasc Electrophysiol 2015;26:520-526.

19. Ferdman DJ, Liberman L, Silver ES. A smartphone application to diagnose the mechanism of pediatric supraventricular tachycardia. Pediatr Cardiol 2015;36:1452-1457.

20. Baquero GA, Banchs JE, Ahmed S, et al. Surface 12 lead electrocardiogram recordings using smart phone technology. J Electrocardiol 2015;48:1-7.

21. Wootton R. Twenty years of telemedicine in chronic disease management—An evidence synthesis. J Telemed Telecare 2012;18:211-220.

22. Flodgren G, Rachas A, Farmer A, et al. Interactive telemedicine: Effects on professional practice and health care outcomes. Cochrane Database System Rev 2015;(9):CD002098.

23. Mortara A, Pinna GD, Johnson P, et al. Home telemonitoring in heart failure patients: The HHH study (Home or Hospital in Heart Failure). Eur J Heart Fail 2009;11:312-318.

24. Dar O, Riley J, Chapman C, et al. A randomized trial of home telemonitoring in a typical elderly heart failure population in North West London: Results of the Home-HF study. Eur J Heart Fail 2009;11:319-325.

25. Chaudhry SI, Mattera JA, Curtis JP, et al. Telemonitoring in patients with heart failure. N Engl J Med 2010;363:2301-2309.

26. Koehler F, Winkler S, Schieber M, et al. Impact of remote telemedical management on mortality and hospitalizations in ambulatory patients with chronic heart failure: The Telemedical Interventional Monitoring in Heart Failure study. Circulation 2011;123:1873-1880.

27. Kitsiou S, Pare G, Jaana M. Effects of home telemonitoring interventions on patients with chronic heart failure: An overview of systematic reviews. J Med Internet Res 2015;17:e63.

28. TEC4Home Healthcare Innovation Community. Supporting heart failure patient transitions from acute to community care with home telemonitoring technology: A protocol for a provincial randomized controlled trial (TEC4Home). JMIR Res Protoc 2016;5:e198. 

29. Yao C, Ho K. Mobile sensors and wearable technologies. In: Amelung VE, Stein V, Goodwin N, et al., editors. Handbook integrated care. Cham, Switzerland: Springer; 2017.

30. Ho K, Borycki E, Kushniruk A, et al. The health perspective in using digital media for health and wellness. Presented at the IEEE International Digital Media Industry Forum, Boston, MA, 4-6 July 2016.

31. Azumio Inc. Instant heart rate. Accessed 28 August 2017. www.azumio.com/s/instantheartrate/index.html. 

32. Azumio Inc. Sleep time. Accessed 28 August 2017. www.azumio.com/s/sleeptime/index.html. 

33. RelaxLine. BellyBio. Accessed 28 August 2017. https://itunes.apple.com/ca/app/bellybio-interactive-breathing/id353763955?mt=8.

34. Ho K. How health information technologies are enhancing health of patients and their doctors. Presentation at the Alberta Medical Association 2015 Spring Representatives Forum, Edmonton, AB, 13 March 2015.


冲击奖项:很难相信斯特里普得不到最佳女主角提名,而汉克斯在销声匿迹几年后,早该获得一项表演类提名了。
1983年的夏天,早熟的17岁少年埃利奥与家人一同在意大利北部伦巴第的17世纪乡间别墅度假。他邂逅了英俊的博士生奥利弗,后者是埃利奥父亲的实习生。那个夏天,一切都沉醉在灿烂阳光中,埃利奥和奥利弗彼此探索着欲望觉醒带来的令人晕眩的美。这个夏天将改变他们的一生。
单词debut 联想记忆:
It remains the world's largest country and the largest oil producer. It retains its permanent seat on the UN Security Council. Its nuclear arsenal (in Cold War times one of five countries, but now one of nine) has been progressively modernised. Sustained increases in defence spending have brought it close to its goal of escalation dominance in local and regional war.
André Aciman’s 2007 novel has spawned a big screen adaptation that’s among the most acclaimed films of the year. Up-and-coming 21-year-old actor Timothée Chalamet plays a young man living in Italy who has a passionate affair with an older academic (Armie Hammer). When it premiered at the Sundance Film Festival in January, BBC Culture critic Sam Adams awarded Call Me By Your Name five stars and praised Chalamet and Hammer’s chemistry, the lush photography of the sun-kissed Italian setting, and the particular nuance and depth of the script. It will be a major Academy Awards contender. Released November 24 in the US. (Credit: Sony Pictures Classics)
人民日报官网表示,2013年符合报考条件的人数到达历史最高——152万,2014年为141万人,这是四年来报考人数首次出现下降。
美国总统唐纳德特朗普(Donald Trump)的零和博弈、“交易艺术”谈判方式,将给那些守旧的现任领导人带来安慰。我希望2018年将提供机会,让正气的、解决问题的新领导人涌现出来。但如果企业领导人因为政治领导层没水平而灰心,变得因循守旧,那么变革可能陷入停滞。
Best Companies rank: 66
米尔德里德的女儿7个月前遇害,但凶手仍然逍遥法外,主角一怒之下做出了一个大胆的决定:买下了小镇入口三张广告牌并在张贴图片中抨击颇有威望的警长威廉?威洛比。威廉的副手官迪克逊是一个幼稚的妈宝男,有暴力倾向。迪克逊卷入这件事后,米尔德里德和小镇执法系统之间的较量变得愈发激烈了。
《警察故事》(Babylon),Sundance,周四播出。詹姆斯·内斯比特(Jame Nesbitt)最近在《失踪》(The Missing)中出演了一个孩子失踪多年、备受折磨的父亲,他在这部剧中饰演的是完全不同的角色:一个斤斤计较的老派警官,雇用一个美国公关专家(布里特·马灵[Brit Marling]饰),来改善苏格兰场的形象。这部讽刺剧集由《贫民窟的百万富翁》(Slumdog Millionaire)的导演丹尼·博伊尔(Danny Boyle)执导,有点像阿尔曼多·伊安努奇(Armando Iannucci)的政治喜剧片《灵通人士》(In the Loop)。

Kendall Ho, MD, FRCPC, Christopher Yao, MSc, Helen Novak Lauscher, PhD. Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health. BCMJ, Vol. 59, No. 10, December, 2017, Page(s) 503-506 - Clinical Articles.



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Selling that many cars would make Tesla larger than the U.S. arms of luxury makers like Lincoln and Porsche, both of which have more diverse product portfolios, long-established dealer networks, and refined strategies for marketing and advertising. Half the sales would come from the aging Model S sedan and the other half the new Model X seven-seat crossover that goes into production early next year.
它促使特朗普当选不仅与选举中的投票数不符,而且也没有反映出亚历山大.汉密尔顿(Alexander Hamilton)想要的那种对候选人德行的判断。
欧盟外交政策高级代表费代丽卡?莫盖里尼(Federica Mogherini)和欧盟扩大事务专员约翰内斯?哈恩(Johannes Hahn)也表明立场,批评埃尔多安提议的宪法改革及其最近的言辞。
One of the best things you can do to improve your entire life, not just school, is meditate. Fifteen minutes a day is all you need to feel calm, centered and confident.

引发收购热议的是一篇路透社的报道,报道援引了一份关于潜在交易的文档作为消息源。实际上,三星已经至少一次地表示过对黑莓的兴趣了,那时还是2012年。而对于最新的谣言,传闻被收购的目标黑莓首先跳出来否认交易正在进行。

  • Only the first three authors are listed, followed by "et al."
  • 红星美凯龙2015年报发布:利润涨幅达20.1%
  • 家具建材市场频现“联盟促销”


Federal, state and local government job cutbacks are slowing. More than 250,000 workers at all levels of government lost jobs last year. This year, so far, about 20,000 have gained jobs. Worries about the nation's debt and deficits likely will keep a lid on government spending and investments, economists say, but any jumps in, say, infrastructure spending would create jobs. At the least, government will be less of a drag.[qh]
Social customer service kills the dreaded phone tree

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