Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health

……叫错面试官的名字。
The captain must steer the ship. If leadership doesn’t know where a project or company is headed, how can the company know? This isn’t just about steps or deliverables, either, but a clear vision of the department or company’s future that he or she can communicate to the employees。
独裁者利用前者作为镇压的借口,利用后者要求绝对服从。
高通:农夫市集走进公司
The crown passed from the Plantagenet dynasty to the Tudor monarchs who painted Richard as a deformed villain who stopped at nothing in his quest for power, even murdering his two young nephews -- the so-called Princes in the Tower -- to secure the throne.
会。目前有很多利好因素:利润、经济增长和美国减税。但这些都是已知因素。按照历史标准看,眼下股价高得离谱,但这对短期走势毫无参考价值。最终还是要看流动性,自从股市在2009年从危机中走出来以后,流动性始终驱动着股市上涨。如果一切按计划进行,到2018年底,各国央行会在缩表和撤除流动性。如果各央行果真这样做,标普500指数很可能会牛气不再。但只要稍有风吹草动,央行官员们就会迟疑。这股牛气应该会继续。
The only things in the way are his staff, Republicans in Congress and the limits of his power. And those are important. Campaign promises of 45 per cent tariffs on Chinese goods have turned into investigations into Beijing’s intellectual property regime.
北方高等商学院毕业生的平均薪酬水平为10.5万美元,排名第11位,而斯隆毕业生为14.36万美元。他们的薪资增幅为79%,排名第七。
本周四公布的一项最新调查显示,近四成美国居民表示,最近发生的桑迪飓风等自然灾害的严重性正是世界末日即将到来的证据,就像《圣经》中预言的那样。而超过六成的受访者认为这是气候变化所致。
“这不是可持续的增长,因为它们并未被租出去,当地市场的喊价者们并不会购买。”
北京首都国际机场的情况稍好一些,其准点率达60.7%。
“尼克是一位优秀的产品思想家,”雅虎移动与新兴产品高级副总裁亚当卡恩(Adam Cahan)说,“他的确代表了他在思索的事物和‘移动’真正内涵的跨世代转变。新一代不仅仅是以移动为先,而且是以移动设备为唯一上网工具。这是一种不同的视角。”
韩云平表示,去年全国的质量监督部门共提交了36000起和违反质量标准有关的案件,涉及金额达23亿人民币(约合3.33亿美元)的货物。
新兴市场GDP增速会超过5%吗?
因此,有如此强大的南美洲队伍坐镇,主要的挑战力量将来自何方呢?嗯,来自欧洲的强势力量恐怕便是最显而易见的答案了,你还能去哪里寻找一个比西班牙更有冠军相的球队呢?作为一支卫冕冠军,并坐拥两届欧锦赛的冠军头号,这是一支不仅知道如何出色发挥,同时知晓如何赢得比赛的队伍。因此,虽然梅西和罗纳尔多曾获得所有年度最佳球员的头衔,但是哈维(Xavi)和伊涅斯塔(Iniesta)却将所有主要冠军据为己有。那么,他们在2014年将延续冠军生涯么?对于这个困扰世界上其他国家的问题,答案是肯定的。不仅大多数老将依然坚守岗位,许多包括科克(Koke )和蒂亚戈·阿尔坎塔拉(Thiago Alcantara)等有才华的年轻球员也加入了。不仅仅如此,他们还从东道主的眼皮下挖走了一个才华横溢的射手蒂亚戈·科斯塔(Diego Costa)收入囊中,因为这位马德里竞技(Atletico Madrid)的前锋选择为西班牙效力,而非自己出生国家踢球。
According to China's business magazine New Fortune's 2018 Chinese wealthy list, the top 10 tycoons' total wealth reached 1.72 trillion yuan, accounting for 18% of the combined wealth of the list's total 500, and the top 10's personal wealth has surpassed 100 billion yuan for the first time.
特斯拉的积压订单达到2.26亿美元。到2014年之前,特斯拉的生产速度大约为每周1000台,也就是说这些订单需要30周才能消化完。
[plein]
《火线警探》,FX,1月20日。副警长瑞兰·吉文斯(Raylan Givens,蒂莫西·奥利芬特[Timothy Olyphant]饰)与他的朋友兼天敌博伊德·克劳达(Boyd Crowder,沃尔顿·戈金斯[Walton Goggins]饰)之间爱恨交织的关系贯穿了整部剧,不管怎样,这个问题将在第六季,也就是最终季中得到最终解决。
福特是硅谷一家软件开发公司的创始人,他认为“或许需要从根本上重建我们的经济规则”,以减轻机器人和自动化的进步带来的冲击。他提出建立保底的基本收入,即“公民红利”,作为一项根本性的补救措施。
"We're excited to have these talented artists showcase the powerful contribution music makes to filmmaking," the show's producers Michael De Luca and Jennifer Todd announced in a statement on Friday. "It's a privilege to welcome them to the 90th Oscars stage."
单词original 联想记忆:
我可能会说:“我解雇你是因为你工作不达标。”实际上,我并不会说是因为你实在让人受不了,每次和人沟通都会得罪人。
单词contain 联想记忆:
老虎要猎食,鸟儿要飞翔;


And while you are at it, don't forget to celebrate the imperfections. While on a 10-day trek in the Himalayas, I learned that imperfections are beautiful too. The rough edges of the mountains, the heavy hail storms in the middle of the afternoon, were "inconvenient" but added to the beauty of the trek. I am acutely aware now that in my pursuit of perfection at work, I have often failed to recognize that imperfections are also a core part of our identity that needs to be preserved and not always changed.
求职者犯的错,他们:
当前油价正在发生什么变化?在业内人士和严肃的投资者中间,对这个问题有两种不同的看法。2016年油价走势或许有助我们看清哪种观点是正确的。


With the increasing proliferation and sophistication of mobile phones, wearable devices such as smart watches, and sensors that can measure and gather a variety of data, public interest is growing in using consumer electronics to take ownership of personal health and wellness. A 2015 survey found that 66% of Americans age 66 and older want to use mobile technologies to improve their health by receiving medication reminders and tracking diet and nutrition, physical activity, and symptoms.[1

Until four years ago, Maddie was an unknown eight year old who enjoyed dancing and went to a local primary school.
长话短说,1772年圣诞节后,Seppenwolde很快就破产了。这场灾难是当时荷兰报纸的头条新闻。它彻底毁了阿姆斯特丹一批商人和银行家。为了防止出现全面的信贷崩溃,阿姆斯特丹市只能作为最后贷款人暂时介入。这种情形是不是似曾相识?
Nineteen buildings disappeared in the space of 10 seconds after being demolished by a controlled explosion in China yesterday.
Hitting the Top 100 for the first time, French fashion brand Dior and Silicon Valley automaker Tesla Motors Inc. were at Nos. 89 and 100 respectively.

Health apps and wearables
Health apps and wearables can unobtrusively gauge physiological and emotional states and collect, quantify, and monitor data regarding a user’s day-to-day behaviors. This “quantified self” can increase users’ self-awareness regarding their behavior and encourage positive changes to their overall health and well-being.[2] These commercially available devices also integrate an array of features to provide motivation through reward systems, opportunities for social in-teraction, tools for self-improvement, and prompts. The novelty, affordability, practicality, and ease of use have resulted in increased consumer enthusiasm and the pervasiveness of these devices.[3,4] With this growing interest in personal health, members of the general public are becoming more involved in monitoring and improving their own health habits.[5-10

Undoubtedly, merely tracking data through a device is not enough to maintain good health-related behaviors long-term, and the software must also incorporate motivational constructs important for the adoption and habituation of behaviors. For instance, a systematic review of studies that considered the use of electronic activity monitor systems found short-term changes in physical activity with self-monitoring, but no demonstration of superiority when the systems were compared with other interventions.[11] Another review of studies on the viability of using mobile technology for measuring and influencing physical activity found that most apps allow users to document their activity, set goals, review real-time feedback, connect to a social support network, and access online expertise.[12] However, less common among these apps were prompts to act and opportunities for problem solving and action planning, which are crucial constructs that translate intention into long-term behavior change.[13]

Sensor technologies
Sensor technologies have begun to enter the telehealth landscape and are primarily focused on continuous monitoring and precise diagnostics to inform management of various health conditions and diseases.[14-17] Sensors can be integrated into a watch or arm band or adhesive bandages and clothing, and then programmed to collect data on cardiac rhythm, heart rate, blood pressure, respiration, oxygen saturation, galvanic skin response, glucose levels, body temperature, body motions, ambient temperature, and global positioning. For health care providers, sensor inputs can permit remote monitoring, real-time teleconferencing, and timely care for patients with chronic diseases. For both patients and clinicians, telehealth supported by sensors can have profound implications. Clinicians can provide timely and patient-centred care to those living at a distance with chronic disease and can coordinate care when multiple providers are involved, reducing costs to the health care system.

A current clinical example is the management of paroxysmal atrial fibrillation with a mobile ECG and app that monitors the patient’s electrical rhythm to detect frequency and patterns of arrhythmias, and may even allow patients to share ultrasound and electrocardiogram data with their health care provider.[18-20] Telemonitoring with sensors can also support self-management of chronic diseases and detect early signs of deterioration in health requiring immediate treatment and advice.[21] Studies to date have demonstrated some clinical promise for the use of home telemonitoring in the context of heart failure and diabetes. A recent Cochrane review found that telemonitoring was an effective way to lower levels of glycated hemoglobin and low-density lipoprotein.[22] Although several studies on heart failure have produced conflicting results regarding the overall benefits of home monitoring,[23-26] systematic reviews have suggested that home telemonitoring reduces all-cause mortality and hospitalizations, and improves quality of life compared with usual care.[22,27] In addition, features such as automated and mobile telemonitoring appear to be more effective compared with other forms of home telemonitoring.[27]

Further studies are needed to determine how home health monitoring can improve patient safety during the transition from acute care to community care, and to examine the impact of home monitoring on health care costs. TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), an initiative of the University of British Columbia and Vancouver Coastal Health, is seeking to do this with prospective trials designed to uncover how telemonitoring can support the safety of heart failure patients discharged from hospital to home.[28]

Mobile apps, wearables, and sensors in the clinical setting
Even though mobile apps, wearables, and sensor technologies are promising, further research is needed to validate their use and long-term impact.[29] This research will require the collaboration of clinicians, health researchers, engineers, and computer scientists.[30] Understanding the possible risks of using these technologies, from physiological harm to breaching of privacy and confidentiality with insecure devices, and how to mitigate any risks is also important. Other important issues to consider include patient anxiety with overuse of technologies, health data piracy, self-diagnosis resulting from overreliance on self-monitoring, and patients not seeking help appropriately. These technologies should be used only as complementary tools in the treatment and prevention of health conditions and disease and should not be used in isolation by patients who self-diagnose and self-manage without consulting a health professional. 

单词capacity 联想记忆:

Instant Heart Rate by Azumio.[31] A free app downloadable to both Apple and Android operating systems that measures heart rate and displays a monitoring strip. As well as helping users accurately track their heart rates, the app is capable of detecting irregular rhythms when palpitations occur. 

Sleep Time by Azumio.[32] A free app that monitors sleep patterns, sleep efficiency, and also acts as an alarm clock. Users can know how often they go into light and deep sleep, and recognize how much of these types of sleep will be necessary for them to feel rested, thereby quantifying the amount of true sleep they need and not just how long they should stay in bed. 

Bellybio Interactive Breating by RelaxLine.[33] A free app that helps users pace their breathing to achieve calmness. Placing the mobile phone against the abdomen, users can follow the sounds emitted to practise deep, abdominal breathing using this simple yet surprisingly effective tool. 

Company: Nation Waste, Inc.
我经常心情沮丧

But the impact of corporate stinginess can go beyond simply ruining employees’ lunar new year holiday, possibly coming back to bite employers: 39 per cent of respondents said they would look for work elsewhere if their year-end bonus was not up to snuff, an increase of 2.3 percentage points from 2015.
圣加伦大学的表现优于上榜的其他商学院,这部分应归功于该校在国际指标上的高分。该校逾90%的学员和80%的教师来自海外。在项目期间学员国际流动性和国际交流方面,圣加伦大学都排名第二。
Song “Friends Forever” (Yang Kun and Zhang Liangying)
Actively expanding China's opening up to the world
Here's how the pay of prime ministers and presidents of the world's biggest economies stacks up, according to official data and converted into US dollars at market rates.
6. “The Martian” With its red-rock buttes and mesas, Ridley Scott’s deeply satisfying space western both draws from an enduring genre and his own Pantheon legacy. (Read the review.)

Discernment to determine whether a particular app, wearable, or sensor can be effective.
Expertise and experience to guide patients on the use of technology.
Partnership with patients in pursuit of optimal health through technology use.
Trials to closely monitor benefits and drawbacks.
Humility to recognize that patients may know and invest much more time than physicians in looking for these tools.34

Conclusions
Based on today’s rapid pace of development and public enthusiasm for the technology marketplace, health apps, wearables, and sensors will soon become integral to our patients’ pursuits of good health and will need to be integrated in clinical practice. Physicians must be active agents in these evolutionary times, guiding patients, advocating for evidence to support the use of technologies, and participating in the development and incorporation of technology in patient wellness journeys. Through clinical stewardship and partnership with patients, physicians can use their expertise and experience to guide the growth of innovations into mainstream health care.

Competing interests
Dr Ho receives no personal financial compensation as the principal investigator of TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), a project funded by a Canadian Institutes of Health Research grant. This grant is matched by the Michael Smith Foundation for Health Research and the BC Ministry of Health, with additional support provided by TELUS Health and Sentrian. TELUS Health, Cisco, and Avizia have also provided equipment for display in Dr Ho’s Demonstration and Simulation Studio for Health (DaSSH) at UBC. Mr Yao and Dr Lauscher have no competing interests to declare.


贵州新型建筑建材业到2020年将超2200亿


References

1. Cision PR Newswire. Fifth annual Pulse of Online Health survey finds 66% of Americans eager to leverage digital tools to manage personal health. Posted 24 February 2015. Accessed 28 August 2017. www.prnewswire.com/news-releases/fifth-annual-pulse-of-online-health-survey-finds-66-of-americans-eager-to-leverage-digital-tools-to-manage-personal-health-300039986.html.

2. Swan M. Emerging patient-driven health care models: An examination of health social networks, consumer personalized medicine and quantified self-tracking. Int J Environ Res Public Health 2009;6:492-525.

3. Gao Y, Li H, Luo Y. An empirical study of wearable technology acceptance in healthcare. Ind Manag Data Syst 2010;115:1704-1723.

4. Kim KJ, Shin DH. An acceptance model for smart watches: Implications for the adoption of future wearable technology. Internet Res 2015;25:527-541.

5. West JH, Hall PC, Hanson CL, et al. There’s an app for that: Content analysis of paid health and fitness apps. J Med Internet Res 2012;14:e72.

6. Abroms LC, Padmanabhan N, Thaweethai L, Phillips T. iPhone apps for smoking cessation: A content analysis. Am J Prev Med 2011;40:279-285.

7. Cowan LT, Van Wagenen SA, Brown BA, et al. Apps of steel: Are exercise apps providing consumers with realistic expectations? A content analysis of exercise apps for presence of behavior change theory. Health Educ Behav 2013;40:133-139.

8. Azar KM, Lesser LI, Laing BY, et al. Mobile applications for weight management. Am J Prev Med 2013;45:583-589.

9. Breland JY, Yeh VM, Yu J. Adherence to evidence-based guidelines among diabetes self-management apps. Transl Behav Med 2013;3:277-286.

10. Lyons EJ, Lewis ZH, Mayrsohn BG, Rowland JL. Behavior change techniques implemented in electronic lifestyle activity monitors: A systematic content analysis. J Med Internet Res 2014;16:e192.

11. Lewis ZH, Lyons EJ, Jarvis JM, Baillargeon J. Using an electronic activity monitor system as an intervention modality: A systematic review. BMC Public Health 2015;15:585.

12. Bort-Roig J, Gilson ND, Puig-Ribera A, et al. Measuring and influencing physical activity with smartphone technology: A systematic review. Sports Med 2014;44:671-686.

13. Rhodes RE, Yao CA. Models accounting for intention-behavior discordance in the physical activity domain: A user’s guide, content overview, and review of current evidence. Int J Behav Nutr Phys Act 2015;12:1-14.

14. Chen M, Gonzalez S, Vasilakos A, et al. Body area networks: A survey. Mob Networks Appl 2011;16:171-193.

15. Appelboom G, Camacho E, Abraham ME, et al. Smart wearable body sensors for patient self-assessment and monitoring. Arch Public Health 2014;72:28.

16. Chan M, Estève D, Fourniols JY, et al. Smart wearable systems: Current status and future challenges. Artif Intell Med 2012;56:137-156.

17. Alemdar H, Ersoy C. Wireless sensor networks for healthcare: A survey. Comput Networks 2010;54:2688-2710.

18. Haberman ZC, Jahn RT, Bose R, et al. Wireless smartphone ECG enables large-scale screening in diverse populations. J Cardiovasc Electrophysiol 2015;26:520-526.

19. Ferdman DJ, Liberman L, Silver ES. A smartphone application to diagnose the mechanism of pediatric supraventricular tachycardia. Pediatr Cardiol 2015;36:1452-1457.

20. Baquero GA, Banchs JE, Ahmed S, et al. Surface 12 lead electrocardiogram recordings using smart phone technology. J Electrocardiol 2015;48:1-7.

21. Wootton R. Twenty years of telemedicine in chronic disease management—An evidence synthesis. J Telemed Telecare 2012;18:211-220.

22. Flodgren G, Rachas A, Farmer A, et al. Interactive telemedicine: Effects on professional practice and health care outcomes. Cochrane Database System Rev 2015;(9):CD002098.

23. Mortara A, Pinna GD, Johnson P, et al. Home telemonitoring in heart failure patients: The HHH study (Home or Hospital in Heart Failure). Eur J Heart Fail 2009;11:312-318.

24. Dar O, Riley J, Chapman C, et al. A randomized trial of home telemonitoring in a typical elderly heart failure population in North West London: Results of the Home-HF study. Eur J Heart Fail 2009;11:319-325.

25. Chaudhry SI, Mattera JA, Curtis JP, et al. Telemonitoring in patients with heart failure. N Engl J Med 2010;363:2301-2309.

26. Koehler F, Winkler S, Schieber M, et al. Impact of remote telemedical management on mortality and hospitalizations in ambulatory patients with chronic heart failure: The Telemedical Interventional Monitoring in Heart Failure study. Circulation 2011;123:1873-1880.

27. Kitsiou S, Pare G, Jaana M. Effects of home telemonitoring interventions on patients with chronic heart failure: An overview of systematic reviews. J Med Internet Res 2015;17:e63.

28. TEC4Home Healthcare Innovation Community. Supporting heart failure patient transitions from acute to community care with home telemonitoring technology: A protocol for a provincial randomized controlled trial (TEC4Home). JMIR Res Protoc 2016;5:e198. 

29. Yao C, Ho K. Mobile sensors and wearable technologies. In: Amelung VE, Stein V, Goodwin N, et al., editors. Handbook integrated care. Cham, Switzerland: Springer; 2017.

30. Ho K, Borycki E, Kushniruk A, et al. The health perspective in using digital media for health and wellness. Presented at the IEEE International Digital Media Industry Forum, Boston, MA, 4-6 July 2016.

31. Azumio Inc. Instant heart rate. Accessed 28 August 2017. www.azumio.com/s/instantheartrate/index.html. 

32. Azumio Inc. Sleep time. Accessed 28 August 2017. www.azumio.com/s/sleeptime/index.html. 

33. RelaxLine. BellyBio. Accessed 28 August 2017. https://itunes.apple.com/ca/app/bellybio-interactive-breathing/id353763955?mt=8.

34. Ho K. How health information technologies are enhancing health of patients and their doctors. Presentation at the Alberta Medical Association 2015 Spring Representatives Forum, Edmonton, AB, 13 March 2015.


Leadership
在所有这些影片中,斯文顿用的是同一个牙齿设计专家——伦敦Fangs F/X公司的克里斯·莱昂斯(Chris Lyons)。他在工作中设计了各种牙齿,包括为坎耶·韦斯特(Kanye West)一个音乐录影带中的一只杜宾犬设计了金色尖牙。
防止虐待动物协会南澳首席检查员安德里亚·刘易斯表示,对工作人员来说这是一件“令人心碎”的事。
Because of her success, she no longer lives anything resembling a normal life.
单词movement 联想记忆:
4. "The Big Bang Theory" (3.4 million)
在接下来几年里,大型住宅楼盘必须遵守第87号本地法(Local Law 87)——该法要求楼盘审核能源使用量,并保持系统以最高效率运行。住宅楼是纽约市最大的温室气体排放源,其排放量占总量的37%。“能源是一大热门话题。楼盘怎样提高能源效率?”管理着超过500处房产的FirstService Residential New York的总裁丹·沃泽尔(Dan Wurtzel)说,“如果运营预算的三分之一来自能源耗费,而现在你可以降低这块成本,那么上涨维护费的压力就减轻了。”
欧洲专利局局长伯努瓦·巴迪斯戴利表示,中国公司专利申请量的增加,反映出中国加速扩张到欧洲、正成为一个知识型的全球创新型国家的事实。
A New Year greeting to cheer you, my good friend.希望新年祝福给你带来欢乐,我的好朋友。
Not all the judges agreed with the book’s proposed solutions but nobody questioned the force of its argument.

Kendall Ho, MD, FRCPC, Christopher Yao, MSc, Helen Novak Lauscher, PhD. Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health. BCMJ, Vol. 59, No. 10, December, 2017, Page(s) 503-506 - Clinical Articles.



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Chicago-based rival AT Kearney is also preparing for a change at the top, with a vote to replace Johan Aurik, who has already served the maximum two terms as managing partner, due to take place in the first quarter of 2018. His replacement will be expected to focus on how to pull AT Kearney out of the ranks of mid-sized players.
Look no further than the title sponsor on their building—Smoothie King, a regional drink shop—to realize that the Pelicans have a serious relevancy problem. (By contrast, the NFL's Saints play in the Mercedes-Benz Superdome next door.)
9、《神奇动物在哪里》
热门行业

据BusinessInsider.com报道,麦嘉华夸张地说,“QE基本上会成为我们下半辈子日常生活的一部分”。麦嘉华还说,2010年在贝南克灾难性试验的早期阶段,他曾给出“美联储奔向QE99”的警告。

  • Only the first three authors are listed, followed by "et al."
  • 海南发行全国首单省级人才租赁住房REITs产品
  • 换房2.0时代来临 二孩政策开启楼市“新纪元”


巴韦贾同意这一结论,他指出,韩国和另一个大宗商品净进口国印度,都是成品油的出口国。以美元计算,这些成品油的价值今年应会上升。
调查显示,75%的顾客都知道可穿戴技术(无论是作为前卫的时尚潮流,还是新时代的技术工具),但是只有9%的顾客有兴趣使用它们。根据调查,仅有2%的人表示自己拥有可穿戴设备,其中大部分都是健身追踪器或智能手表。

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